LGD 4033 (Ligandrol): Benefits, Cycles, Dosage & Side Effects

Updated on November 24, 2020

Ligandrol is a therapeutic compound that falls into the category called Selective Androgen Receptor Modulators (SARM). It is also known as Anabolicum, VK5211, and LGD 4033. Ligandrol has responded positively to the treatment of muscle wasting and the growth of muscle mass.

Ligandrol is known to be capable of improving bone density and increase the testosterone level. This drug can address muscle dystrophy and osteoporosis. Therefore, it is considered to heal conditions arising out of various cancers and cancer treatments.

San Diego based Ligand Pharmaceuticals discovered the compound Ligandrol. At present, California based Viking Therapeutics is continuing further research on it. This product has been in business since mid-2015 and available on online platforms. From a regulatory perspective, it is categorized in the US as an investigational new drug.

What is Ligandrol?

Being a SARM, it attaches to the correct androgen receptors without harming other vital organs. It avoids interaction with the tissues of important organs like heart, prostate, colon, and sebaceous glands. It links up with muscles and bones with better precision and selectivity than common steroidal products. Thus in terms of effect, Ligandrol has a proven record.

It is used to build the mass of muscles and help in the reduction of fat. It is increasingly popular among weight trainers and bodybuilders. They use it in short cycles, followed by Post Cycle Therapies. There are signs of clinical hope in Ligandrol’s performance. This is reflected in the research on it as a drug for cancer recovery.

How to Use Ligandrol?

As it has an average half-life of around 30 hours, Ligandrol should not be taken more than once in a day. For best results, Ligandrol can be used in doses of 5 mg to 10 mg on a single day. However, the optimal dose will also depend on the build and metabolism of the user. The recommended daily dosage for women is 5 mg.

To attain significant growth a cycle of 8 to 12 weeks is sufficient. Ligandrol is known to show good results in shorter cycles. Every single cycle must be ideally followed by a Post Cycle Therapy. Post Cycle Therapy helps in keeping the bodily balance and muscle mass intact.

Significant progress can be made with even a very low dose of Ligandrol. A dose as low as 1 mg per day was able to demonstrate a reasonable difference in mass growth. The timing of the dose is not significant. It can be taken before or after food, or on an empty stomach.

Ligandrol: Highlights

A Ligandrol tincture contains high-quality Ligandrol in liquid form. It has to be taken only as per the recommended dosage and intervals. Apart from the purity of the tincture’s content, the optimum dosage is also crucial to avoid side-effects. Post Cycle Therapy is recommended after each Ligandrol usage cycle.

The use of Ligandrol shows positive results in lean muscle growth and an increase of bone growth. Its low interference with hormone levels rules out the possibility of anomalies like enlarged prostate. Apart from lean muscle enhancement, Ligandrol also reduces body fat. It is also known to enhance energy, stamina, and speed of the user, apart from its therapeutic benefits. Major therapeutic benefits include its prospective use in the treatment of muscle mass and strength loss due to old age. Considerable research has been ongoing on the use of SARMs like Ligandrol in the treatment of muscle wasting.

Ligandrol demonstrates a high affinity towards muscle building androgen receptors. They are known to have little to no interaction with other androgen receptors in the body. As a result, it has an impressive anabolic to androgenic ratio of 10:1. It is known to have a half-life of 24-36 hours. Being available in liquid form, Ligandrol can be taken orally by the user.

How Does Lignadol Works?

As a compound, Androgen nurtures the male characteristics in the body. To do so, it binds with androgen receptors present in the cells. Ligandrol or LGD 4033 is a Selective Androgen Receptor Modulator (SARM). Being a SARM, it has a natural tendency to bind with androgen receptors. However, it is selective in its targets. Unlike most steroids, it binds to the androgen receptors in the muscles. Its selective affinity makes it a better muscle building option for you. Ligandrol triggers a tissue-selective activation of the androgenic signalling process. Testosterone is a major ligand for the androgen receptor that enables various physiological activities in the human body. However, SARMs like Ligandrol are getting attention because of their anabolic properties. These properties stand to benefit the muscle and bones in particular.

Ligandrol has been developed out of researches that ingrain the desired activity profile and tissue selectivity. Therefore, it can work without disturbing the functioning of vital organs like the liver and prostate. Its tissue selectivity ensures that the natural testosterone level in the body is not reduced. So far it has been concluded that Ligandrol doesn’t aromatize into estrogen in the course of its activity. Besides, it also doesn’t convert into Dihydrotestosterone, a testosterone metabolite. Due to this dual safeguard, Ligandrol avoids side effects like male breasts, hoarse voice, additional body hair, prostate problems etc.

Ligandrol targets anabolic pathways that safeguard the muscles from breakdown. Thus it helps maintain muscle growth even after your efforts to get cuttings and in case of low-calorie intake. Apart from normal muscle wasting, Ligandrol is also responsive in cases of extreme muscle wasting. In Cachexia like situations, Ligandrol stops muscle wasting without leading to after-effects like increased risk of prostate cancer, liver toxicity, female masculinization, etc. Testosterone and anabolic steroids cannot guarantee this safety.

Ligandrol Benefits

The following benefits sum up why you can use Ligandrol,

  • It increases muscle mass,
  • It can increase bone density and strength,
  • It can accelerate the recovery of bone and muscle mass,
  • It can have a stimulating effect on your general well-being.

Ligandrol Side effects

Although widely regarded as safe, it may have side-effects. Most of these tend to wear down with regular use, like,

  • Headache,
  • Dry mouth,
  • Fatigue,
  • Nausea.
  • To avoid hormone suppression, avoid longer cycles and higher doses.

Where to Buy Ligandrol From?

Ligandrol can be bought from Proven Peptides and you can read the features of this Ecom site below:

Lab Tests and Results

Lab results have shown Ligandrol as safe and well-tolerated by the human body. The increase of lean mass was noted without changes in the prostate-specific antigen levels. No changes were observed in hemoglobin and aminotransferase levels. There are no serious side-effects of Ligandrol. Lab tests conducted by the National Center for Biotechnology Information didn’t observe any drug-related adverse effects.

Dose-dependent suppression of total testosterone was noted. Users apply Post Cycle Therapy to cope with the same. Hormone and lipids returned to their normal level upon discontinuation of its use. It was seen to have a favorable pharmacokinetic profile.


The shipping timeline is clarified to you in advance by the dispatching store. At present this product is available online only. Exact shipping cost and timeline will depend on the seller’s policies. Do note that when bought from an unverified source, Ligandrol can show adverse after-effects. This is due to the illicit mixing of steroids by the seller.

There is no restriction on the sale of Ligandrol if used for research purposes. However, many sporting authorities discourage it as a performance-enhancing drug. It is listed in the ‘Other Anabolic Agents’ class of the WADA Prohibited List. Concerned professional athletes may avoid its use for competitive purposes.

Return Policy

The return policy will depend on the terms and conditions of the seller. Established sellers like Sarms4You provide a 14-day window for return. They return the purchase cost, while you will have to bear the cost of return shipping. Such returns are accepted only if the sold unit of Ligandrol is returned to us in unused and original condition. The return may be required to be made along with the original packaging and invoice.

The settlement of refund against your return if these conditions are fulfilled. The refund timeline is also clarified at the time of purchase.

Conclusion: Should you go for Ligandrol?

The use of Ligandrol purchased from a recognized vendor yields excellent results. They have very little side effects. Minimal dosage over a short period is sufficient to give satisfactory growth. The choice of Ligandrol will depend on your specific goals. But it is an easy choice against other supplements and boosters.

It has been discovered and researched by reputed pharmaceutical research companies. That adds to the authenticity and safety of Ligandrol. And all this makes Ligandrol a better recommendation compared to other growth supplements.

We advise you to procure a third-party tested Ligandrol, distributed by a name you can trust upon. You should follow the proper dosage and duration cycle of Ligandrol. Thereafter, you can bank on Ligandrol to give you the growth you always desired. It is the ideal choice if you want growth without using steroids.

Ligandrol activates the androgen receptors improve the bone mineral density in the body. It also leads to periosteal reactions in the body that aids the formation of new bones, increasing their healing capacity. For all the effects of Ligandrol, it makes very little alteration in the prostate-specific antigen levels.

Ligandrol Frequently Asked Questions

Is Ligandrol a steroid?

Ligandrol is a SARM. It is different from steroids, particularly when it comes to side effects. It is not known to have the harmful effects of steroids.

How is Ligandrol safer than steroid?

Being a SARM, Ligandrol binds with androgenic receptors on a selective basis. By doing so it avoids harming vital organs, which steroids cannot. Steroids aromatize in the human body while SARMs like Ligandrol doesn’t. So unlike steroids, it doesn’t cause any harmful effects on hormone levels.

Is it illegal?

No, it is not illegal. It is available on various websites and can be marketed for research purposes.

Can Ligandrol be bought without a prescription?

Yes, no prescription is required to purchase Ligandrol. It can be easily ordered from any reliable online seller that sells Ligandrol.

Can I buy Ligandrol from any online or physical store?

Yes, Ligandrol is sold by several online sellers and resellers. SARM vendors like Science. Bio, Sarms4You, Umbrellalabs.is, and Secretsupps often come up in reviews as reliable vendors.

Can I receive Ligandrol in discreet packaging?

The packaging and labeling will vary from seller to seller. However, you can use the “order notes” or similar request boxes in the checkout page to instruct the need for discreet packaging.

Why is Ligandrol used?

Ligandrol is used mostly by bodybuilders and workout enthusiasts to build muscle mass. It is also used to ensure strength, faster repair from muscle waste, and recovery.

Can it be used along with other supplements?

People stack Ligandrol with body recomposition supplements like Cardamine. It gives them leaner and harder muscles with lower water retention. Those looking for cuts also use it while following a calorie-controlled diet regimen.

What are its side effects?

Ligandrol users may face very mild side effects, none of which are permanent. It includes nausea, dry mouth, fatigue, and a slight headache. Heavy dosage over a longer period can suppress testosterone, follicle inducing hormones and other sex hormones.

Can it be used by professional athletes?

Ligandrol, like other SARMs, is not allowed by the World Anti-doping Agency. Therefore professional athletes can risk disqualification if they use Ligandrol.

Why is Ligandrol better than anabolic steroids?

Being a SARM, Ligandrol doesn’t cause the effects of aromatization and masculinization. It also doesn’t cause mood alteration, skin problems, and hair loss, unlike anabolic steroids.

Is Post Cycle Therapy required with Ligandrol?

Post Cycle Therapy after each Ligandrol cycle is recommended. It keeps the hormone levels intact and ensures that hormone-secreting glands are running normally.

Does Ligandrol lead to an increase in testosterone?

No, it doesn’t. Ligandrol can lead to a dose-dependent suppression of total testosterone.

How long does it take Ligandrol to show results?

Ligandrol can show its results quite quickly. You can see a positive result in the growth of lean muscle as early as two to three weeks.

How long does Ligandrol remain in the human body?

It has a half-life of 24-36 hours. Thus, its presence continues to drop by half with every such interval. For someone taking a 10 mg dose of Liganrol, its traces will remain for 7 days. While the metabolites can be found with precise instruments for even up to 21 days. Normal hormone level returns to the baseline in about 56 days after discontinuation.

What do I keep in mind while buying Ligandrol?

The buyer has to ensure genuineness by looking at the reviews, ingredients, reputation of the seller, etc. You should also make sure that the product has been analyzed by a third party. Prior communication with the seller can also try to understand them and the product better.

Who cannot/shouldn’t use Ligandrol?

It is used by bodybuilders and fitness enthusiasts. So if you don’t have an active workout schedule, Ligandrol will not be advisable for you. That would include people like pregnant women, lactating mothers, people with medical conditions, etc. It should not be used by professional athletes as it is banned by the sport’s governing body WADA. People on medication should not use Ligandrol without prior consultation with doctors.

Are there any shipping costs?

The shipping costs will depend on the seller’s terms and conditions and the location of the buyer. For example, shipping may be made free over a certain amount, as in the case of Sarms4You. They charge a flat 15.99 euros on every purchase below 120 euros.

How is the payment made?

Payments to recognized sellers like Sarms4You provide a wide range of payment options. It includes card payments, bank transfer, virtual payments like wallets and bitcoins, etc. They also offer EMI options to select locations.

Do Ligandrol sellers provide sufficient information to the buyer?

Yes, most established sellers provide all necessary information to the buyer on their pre-sales page. It includes information like chemical and molecular information, contents, terms, and conditions, etc. In the absence of any necessary information, the seller should be asked for such information on an official chain of communication.