Clinical efficacy of Soma pill

0
14

Saint Augustine quotes,“The greatest evil is Physical pain”

efficacy.png

Body pain is a common problem worldwide that causes deterioration of the health and quality of life. Suffering from back pain is usually associated with muscle spasm. Many factors can be associated with chronic pain thus contributing to increasing the care cost of the person. According to the reports published by the Centers for Disease Control and Prevention, an estimate of 20.4% of the adults in the United States suffers from chronic pain. This condition is seen to be more prevalent in adults living in poverty. Working and functioning can be largely impaired when down with body pain. Thus, most physicians’ advice to use the Soma pill to help fight acute pain. This high percentage of people with body aches is a reason for the rise in the Carisoprodol market and people buying Carisoprodol. Pain can be defined as an unpleasant stimulus that threatens the homeostasis of a person. Suffering from pain is seen to affect a person both physically and mentally. Therefore, fighting body pain is a very important factor to live a normal and healthy life. One of the most common questions that arise in the mind of the person is that, why choose Soma pill? Or how does Soma pill differ from other analgesics? Let us have a glimpse of the efficacy of Soma pill as a muscle relaxant. 

How does Soma pill differ from other analgesics?

Soma is the trade name for Carisoprodol. This on reaching the body of the person gets converted to meprobamate in the liver of the person. The meprobamate was originally developed to treat anxiety in people. In the year 1957, about 36 million prescriptions were written for Soma pill. This is a muscle relaxant that specifically targets the skeletal muscle of the person. It helps by blocking the pain receptors from reaching the brain receptors of the person. Thus, the person does not feel the sensation of pain after taking Soma dosage. What makes it better than the other analgesic available in the market is its efficacy and the fast-acting formulation. The action of Soma pill begins to work within thirty minutes of intake and its action lasts for 5 to 6 hours depending on the person taking the medication.

The link between depression and body pain

One of the most common physical symptoms seen in people with depression is vague aches and pain. They also include limb pain, joint pain, tiredness, back pain, and appetite change. It is seen that a high percentage of patients with depression complain about body ache. Researchers suggest physical pain and depression have a deep biological connection. The neurotransmitter that affects both the sensation of pain in the body along with mood is serotonin and norepinephrine. Going by the research reports by Madhukar H. Trivedi, National Center for Biotechnology Information, patients with severe body ache are more likely to suffer from a mood disorder. Carisoprodol when gets metabolized by CYP2C19 to meprobamate helps in treating anxiety and helping in uplifting the mood of the person. Thus, being very effective in depression. 

depression vs body pain.jpg

In the graph based on a study by Kroenke et al, shows the case study of 1000 patients. In patients who report 0 to 1 physical symptom or sign of body ache, 2% of the patients showed a sign of mood disorder. Whereas, in people with higher physical symptoms about 60% of the people were found to suffer from mood issues. 

Safety of Carisoprodol during pregnancy

Pregnancy is a very crucial phase in a women’s life. It is very important to take precautions and check before consuming anything. Doing so can affect the health of the fetus as well. The FDA categorizes medication based on safety during pregnancy. They are divided into five categories- A, B, C, D, and X. Carisoprodol belongs to category C. This means that the Soma pill can be given to pregnant women but under a doctor’s supervision. According to a research report by Gerald G Briggs, when 28 years woman with severe back pain was given carisoprodol 2800mg/day before pregnancy and while breastfeeding showed only mild sedation was seen in the infant. 

The danger of mixing Soma pill and alcohol

Soma pill has a potential for abuse as the effects of the medication sets in quickly and lasts for four to six hours in a person. Soma pill is known to increase the high of other substrates. Therefore, when the Soma pill is taken with Alcohol, it increases its effect on the person. It is seen that alcohol is frequently taken in combination with other intoxicating substrates that regulate and enhances the intoxication that the person experience. However, doing so can be very dangerous and affect the health of the person drastically. 

On mixing alcohol with Carisoprodol can lead to the following symptoms in a person-

  • Drowsiness 
  • Headache
  • Nausea
  • Stomach upset
  • Hiccups
  • depression
  • Irritability 
  • Blurry vision
  • Insomnia 
  • Agitation

Why do people mix Soma pill with alcohol?

soma alcoohol.png

Both Soma pill and alcohol interact with the GABA receptors in the brain thus resulting in the slowing down of the brain reacts to stimuli. It also prevents the reuptake of the neurotransmitter to cause relaxation in the mind of the person. The use of Carisoprodol is also very effective in relaxing the skeletal muscle of the person. The interaction of GABA with interrupted neutral communication leads to full-body relaxation in the person along with the feeling of being high. Thus, many people prefer to mix soma with alcohol for recreational use. 

A pharmacological study of Carisoprodol abuse in Norway 

Carisoprodol is a very potent muscle relaxant that helps with moderate to severe acute pain. But using Soma pill for more than three weeks at a stretch can cause dependency in a person. The other factor that contributes to the dependency and addiction to Soma pill is taking a dosage higher than the recommended ones. Therefore, it is advisable to take the Soma dosage that is prescribed to you and not continue it for more than three weeks. 

According to research done by Jorgen G Bramness, the Norwegian prescription database contains the information of the patient’s prescribed Soma pill. In such people, a high level of Carisoprodol use can indicate abuse or development of tolerance. A study was carried out seeking the behavior of people using Soma pill. This was then compared with a series of other medicines. 

soma abuse.jpg

The graph here shows the age and gender-specific prevalence or commonness related to the total population of age 18 years or more. It is seen that in the year 2004, 53889 women and 29824 men in Norway received at least one prescription for Soma pill. The female users were more and also received a larger mean amount compared to the men. Of the 83713 users, 62% were buying carisoprodol online for therapeutic use. 16% were taking it for pseudo-therapeutic long-term use and 1% were characterized as pure Carisoprodol abusers. 

If you are suffering from severe body ache and planning to buy Soma pill then there is not much to worry about. The use of the Soma pill is completely safe if taken in the right dosage. You can take Soma pill for 3 to 4 times a day depending on the severity of the condition. However, make sure that you do not suddenly stop its usage and rather first lower the dosage gradually.