Proven Peptides Review: Peptide Therapy Used to Treat Brain Injury

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According to the Center for Disease Control & Prevention, traumatic brain injury (TBI) is a cause of lots of disability and impairment in the United States. TBI may be caused by a head blow or shock.

Traumatic brain injury is also a risk factor that can lead to a person getting Parkinson’s disease, as can be illustrated by Muhammad Ali’s PD diagnosis in his boxing career. 

What is Traumatic Brain Injury? 

TBI is a brain injury caused by a jolt, blow or shock to the head from penetrating or blunt force. The damage that occurs immediately when the accident happens is called primary injury. Primary injuries may involve the whole brain or a specific lobe. Sometimes it may cause a skull fracture.

During the incident, the brain smashes forth and back inside the skull causing bleeding, nerve fiber tearing, and bruising. The person may immediately get confused, have dizziness and blurry vision, lose consciousness, and unable to remember what happened. 

The brain experiences a delayed trauma. It swells, pushes itself from the skull hence lowering oxygen/blood flow – a condition known as secondary injury.

Classification of Brain Injury

When the brain is injured, it can be categorized according to the following severity:

Mild: The person is awake, eyes are open. Signs include confusion, memory loss, headache, slight loss of unconsciousness, and disorientation. 

Moderate: The victim is sluggish. With stimulation, eyes can open. Symptoms include a longer period of loss of consciousness (lasting 20 min – 6 hours), brain bleeding, or swelling that causes sleepiness. 

Severe: The victim is unconscious; eyes can’t open even when stimulated. Consciousness loss lasting for over 6 hours. 

Peptide therapy plays a very important role in the treatment of traumatic brain injury for its complete cure. The following is a review of proven peptides known to cure injury of the brain arising from blunt, shock, or penetration force.

Peptides for Treating Brain Injury 

Cerebrolysin 

It improves TBI patient’s functional outcomes. The administration of Intravenous Cerebrolysin helps in the recovery of mild, moderate, and severe injuries. 

LOCKR 

This peptide modulates injury’s response to the immune system and checks upon inflammation. 

Neuropeptides 

Lowers the fluid in the blood-cerebrospinal, functional deficits, and brain pathology following TBI.

Peptide Hydrogel 

It helps in blood vessel regrowth, hence improving neuronal survival. By this self-assembling hydrogel, the blood may accumulate glutamate, which kills neurons – a process known as glutamate-dependent neurotoxicity.

To limit brain secondary damage immediately after an injury occurs, medication may include:

Diuretics

Diuretics lower the tissue fluid amount hence increases urine output. It helps in pressure reduction in the brain. 

Anti-Seizure Drugs 

They are taken in the first week of injury to avoid more brain damage caused by seizures. Anti-seizure drugs are continuously taken if the seizure is recognized. 

Coma-Inducing Drugs 

Since a comatose brain doesn’t require much oxygen to function, some physicians put injured victims in a temporal coma by use of drugs. This is usually done if blood vessels are unable to supply normal and enough oxygen and nutrients into the brain cells. 

Special Care Treatment in Collaboration with Peptides

Special care needs to be administered in collaboration with peptides for a complete cure solution. This care is given based on the severity of the injury.

Mild Injury

Mild brain injuries require no treatment save for over-the-counter pain relievers and some rest. Nevertheless, mild brain injuries need close monitoring in case it worsens, new symptoms develop, or the condition becomes persistent

The victim may need to follow up with a doctor’s appointment. The issue of when to resume work, recreational activities, or school should be authorized by the doctor. 

Moderate Injury 

Ensure the victim gets adequate blood supply and oxygen, prevent further injuries to the neck or head, and maintain normal blood pressure. 

Severe Injuries 

Severely injured victims may have other injuries to be addressed. There is a need for additional treatments in the care unit which ought to focus on secondary damage minimization due to low blood/oxygen supply to the brain.

What Are the Types Of TBI?

Diffuse Axonal Injury (DAI) 

Nerve cells stretching and shearing at the cellular level. It happens when blood rapidly moves forth and back in the skull, damaging and tearing nerve axons. 

Hematoma 

This is a blood vessel rapture. When some blood escapes the normal flow of the bloodstream, it thickens and clots. Clotting helps to stop bleeding. 

Traumatic Subarachnoid Hemorrhage (TSAH) 

Bleeding in the space in between the brain and skull. This space fills with cerebrospinal fluid (CSF), a cushion-like fluid that protects the brain. This type of injury occurs whenever a minor artery breaks during the first injury. 

Contusion 

It’s a bruise to a particular brain location caused by head impact; also known as contrecoup or coup injuries

Concussion 

This is a slight injury in the head. It may lead to loss of consciousness, but the injury may not be serious. 

What Are the Signs and Symptoms?

  • Fatigue 
  • Seizures 
  • Vomiting 
  • Headaches 
  • Visual problems
  • Sleep disturbances 
  • Poor concentration 
  • Feeling of depression 
  • Loss of consciousness 
  • Loss of balance/dizziness
  • Amnesia/ memory loss
  • Disorientation and confusion 

How Can You Prevent Brain Injury?

  • When playing sports, put on protective headgear.
  • Lock firearms in a cabinet and store their bullets separately 
  • Exercise more to increase body balance, coordination, and strength, to avoid falls.
  • Avoid driving under drugs and alcohol influence 
  • Keep all the house items in their rightful places, to avoid falls
  • Wear your seat belt always 
  • Put on your helmet when riding a motorcycle, skateboard, bicycle, or a vehicle 

Traumatic brain injury is a serious condition. Survivors may encounter depression and impaired motor control. Victims of TBI should be treated with a lot of care. Use Cerebrolysin, a valuable, trusted solution peptide for regenerative therapy.