Protein is one of the building blocks of all organisms. Each molecule of protein has one or more polypeptide chains of amino acids. Amino acids linked in series by peptide bonds form protein chains. Proteins aid in a wide range of biological functions within organisms, including enzyme catalysis, motion, defense, and support.
Earlier, to get a specific protein, it had to be isolated from a natural source. However, with recent advancements in the recombinant molecule, biological techniques have made possible the cloning of DNA encoding of a specific protein.
Recombinant proteins (rec. protein) are a manipulated version of proteins generated in different ways to produce large amounts of proteins and useful commercial products. The formation process of a recombinant protein is in specialized vehicles known as vectors. Let’s now see the reasons to choose these proteins over the commercial types.
Control Over the source
With rec. proteins, you can identify where your protein is produced and by what. Further, you can also see detailed specifications on the lines of purity, diluent, stability, molecular weight, and physical state.
The production of such proteins caters to your exact requirements. Also, you get the guarantee that the future batches will iterate the same procedure. The variability factor among different batches is low, ensuring consistent production and hence excellent reproducibility.
Reproducible Biological Activity
A unique production source ensures less batch-to-batch variability. The manufacturers remain the same; thus, there is no risk of supply changes. It affirms all products meet a high standard of quality in terms of purity, specificity, and biological activity. Since the manufacturers validate each batch, it saves your time, guaranteeing you the quality.
Furthermore, some commercial types do not undergo biological testing. You will have to invest your time and money in testing and validation procedures. The results may not be fruitful since these proteins will not fulfill all your requirements.
Growing Demand for Rec. Proteins for Therapeutic Applications
Many human diseases categorically or partially relate to the dysfunction of specific proteins. Therapeutic proteins provide vital therapies for various conditions, like cancer, diabetes, hemophilia, infectious diseases, and anemia. Generally, therapeutic proteins consist of FC fusion proteins, antibodies, enzymes, hormones, and anticoagulants.
There is a massive demand for recombinant proteins for therapeutic applications. Human proteins obtained from genetic engineering play a pivotal role in the therapeutic medicines market.
Bring in Feasibility
At times, you may face issues in your applications based on reagents. Rec. protein production does not make any exception. Depending on the nature and affinity of secondary detector reagents, you can alter the protein concentration. A dose-specific response analysis identifies the optimal protein concentration for use in specific applications.
Add Flexibility with Safer Options
Typically, manufacturers come up with rec. protein variants of a wide variety of specialty biologicals for Human T-cell Research/ Diagnostics, AIDS, Cancer, TB, and therapeutics development. Thus, it brings in flexibility in your application, where you can work with the protein variant best suitable for your requirement.
Furthermore, the manufacturers emphasize the use of biologicals/biochemicals, classified as non-hazardous (MSDS) for the manufacturing of products, ensuring safety.
Aggressive research and development in rec. proteins have made it a superior option over the commercial types.